Compound Detail
CHEMBL5286462
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Basic Information
| ChEMBL ID | CHEMBL5286462 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | JKERKMVDMJATJW-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
239.6
MW (Da)
1.41
ALogP
3
HBA
1
HBD
44.7
PSA (Ų)
0.74
QED
0
Ro5 Violations
0
Rot. Bonds
Drug Information
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
EC50 1 meas. best 7.47
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| HeLa CHEMBL399 | EC50 | 7.47 | 7.47 | 34.2 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| HeLa | EC50 | = | 34.19 | nM | 7.47 | Cytotoxicity against human HeLa cells assessed as reduction in cell viability af... | 37077378 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 37077378 | 10.1021/acsmedchemlett.3c00092 | HeLa | 1 |
Data from ChEMBL 36 via Core Engine