Compound Detail
CHEMBL5289712
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Basic Information
| ChEMBL ID | CHEMBL5289712 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | SMCCEKIOJYIRLQ-XQFMJXHWSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
405.5
MW (Da)
3.87
ALogP
4
HBA
0
HBD
28.1
PSA (Ų)
0.76
QED
0
Ro5 Violations
2
Rot. Bonds
Drug Information
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
EC50 1 meas. best 6.64
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Unchecked CHEMBL612545 | EC50 | 6.64 | 6.64 | 231.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Unchecked | EC50 | = | 231.0 | nM | 6.64 | Induction of progranulin secretion in mouse BV-2 cells | 36368496 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 36368496 | 10.1016/j.bmcl.2022.129048 | Unchecked | 1 |
Data from ChEMBL 36 via Core Engine