Compound Detail

CHEMBL5314374

IDRAPARINUX SODIUM

🧪 Phase III

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🧪 Phase III

CO[C@H]1O[C@H](COS(=O)(=O)[O-])[C@@H](O[C@@H]2O[C@@H](C(=O)[O-])[C@@H](O[C@H]3O[C@H](COS(=O)(=O)[O-])[C@@H](O[C@@H]4O[C@H](C(=O)[O-])[C@@H](O[C@H]5O[C@H](COS(=O)(=O)[O-])[C@@H](OC)[C@H](OC)[C@H]5OC)[C@H](OC)[C@H]4OC)[C@H](OS(=O)(=O)[O-])[C@H]3OS(=O)(=O)[O-])[C@H](OC)[C@H]2OC)[C@H](OS(=O)(=O)[O-])[C@H]1OS(=O)(=O)[O-].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+]

ChEMBL ↗ Properties Compare Identifier

Basic Information

ChEMBL ID	CHEMBL5314374
Name	IDRAPARINUX SODIUM
Phase	Phase III
Structure Type	MOL
InChI Key	MVPQUSQUURLQKF-MCPDASDXSA-E
Parent Compound	CHEMBL5314801
Active Moiety	CHEMBL5314801

Known Names

Idraparinux de sodio Idraparinux nonasodium salt Idraparinux sodique Idraparinux sodium ORG-34006 SANORG-34006 SANORG34006

Targets

Activities

Assay Types

PK Parameters

Publications

Known Names

Indications

Mechanisms

Molecular Properties

1529.3

MW (Da)

Drug Information

Molecule Type	Oligosaccharide
Chirality	Single Enantiomer

USAN Stem	-parinux
USAN Year	2004

Extended Properties

Molecular Formula	C38H55Na9O49S7
MW	1727.19

Mechanism of Action

Mechanism	Action Type	Target	Direct	Efficacy
Coagulation factor X inhibitor	INHIBITOR	Coagulation factor X	✓	✓

Indications

Atrial Fibrillation Pulmonary Embolism Venous Thrombosis

Activity Summary

Kd 1 meas. best 9.0

Target Activity Profile

Target	Type	Best pChEMBL	Mean pChEMBL	Best (nM)	# Data
Antithrombin-III CHEMBL1950	Kd	9.0	9.0	1.0	1

Activity Data Samples

Top measurements by pChEMBL value

Target	Type	Rel.	Value	Units	pChEMBL	Assay	PubMed
Antithrombin-III	Kd	=	1.0	nM	9.0	Binding affinity to antithrombin 3	20503967

Literature References

PubMed	DOI	Target Context	# Activities
20503967	10.1021/jm100146h	Antithrombin-III	1

Data from ChEMBL 36 via Core Engine