Compound Detail
CHEMBL5314934
VANZACAFTOR 💊 Approved Drug
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
💊 Approved Drug
CC1(C)C[C@@H]2CCCNc3cccc(n3)S(=O)(=O)NC(=O)c3ccc(-n4ccc(OCCC5C6(CC6)C56CC6)n4)nc3N1C2
Basic Information
| ChEMBL ID | CHEMBL5314934 |
| Name | VANZACAFTOR |
| Phase | Approved |
| Structure Type | MOL |
| InChI Key | VCSUIBJKYCVWNF-NRFANRHFSA-N |
| Therapeutic | ✓ Yes |
0
Targets
0
Activities
0
Assay Types
0
PK Parameters
0
Publications
3
Known Names
1
Indications
1
Mechanisms
Molecular Properties
617.8
MW (Da)
4.55
ALogP
10
HBA
2
HBD
131.3
PSA (Ų)
0.42
QED
1
Ro5 Violations
5
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| First Approval | 2024 |
| Availability | Prescription |
| Chirality | Single Enantiomer |
Mechanism of Action
| Mechanism | Action Type | Target | Direct | Efficacy |
|---|---|---|---|---|
| Cystic fibrosis transmembrane conductance regulator positive modulator | POSITIVE MODULATOR | Cystic fibrosis transmembrane conductance regulator | ✓ | ✓ |
Indications
Cystic Fibrosis
Data from ChEMBL 36 via Core Engine