Compound Detail
CHEMBL5394951
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL5394951 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | ZHXFXFODFHJFKJ-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
3
Publications
0
Known Names
Molecular Properties
385.4
MW (Da)
Drug Information
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 6.45
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Replicase polyprotein 1ab CHEMBL4523582 | IC50 | 6.45 | 6.45 | 356.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Replicase polyprotein 1ab | IC50 | = | 356.0 | nM | 6.45 | Inhibition of SARS-CoV-2 MPro using protease substrate preincubated with enzyme ... | 37972434 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 37972434 | 10.1016/j.bmc.2023.117531 | Replicase polyprotein 1ab | 2 |
| 37972434 | 10.1016/j.bmc.2023.117531 | SARS-CoV-2 | 1 |
| 37972434 | 10.1016/j.bmc.2023.117531 | Vero C1008 | 1 |
Data from ChEMBL 36 via Core Engine