Compound Detail
CHEMBL5397977
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Basic Information
| ChEMBL ID | CHEMBL5397977 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | VHJDURJXGVLLBA-FYWRMAATSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
3
Publications
0
Known Names
Molecular Properties
458.5
MW (Da)
Drug Information
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 4.46
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| HCT-116 CHEMBL394 | IC50 | 4.46 | 4.46 | 34400.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| HCT-116 | IC50 | = | 34400.0 | nM | 4.46 | Cytotoxicity against human HCT-116 cells assessed as reduction in cell viability... | 37036951 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 37036951 | 10.1021/acs.jmedchem.2c01808 | HepG2 | 1 |
| 37036951 | 10.1021/acs.jmedchem.2c01808 | HCT-116 | 1 |
| 37036951 | 10.1021/acs.jmedchem.2c01808 | NCM460 | 1 |
Data from ChEMBL 36 via Core Engine