Compound Detail
CHEMBL5398088
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Basic Information
| ChEMBL ID | CHEMBL5398088 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | YPUCLMJFNPCGLW-BZUAXINKSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
279.4
MW (Da)
0.72
ALogP
4
HBA
3
HBD
63.9
PSA (Ų)
0.67
QED
0
Ro5 Violations
6
Rot. Bonds
Drug Information
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 1 meas. best 5.66
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Lysosomal alpha-glucosidase CHEMBL2608 | Ki | 5.66 | 5.66 | 2200.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Lysosomal alpha-glucosidase | Ki | = | 2200.0 | nM | 5.66 | Binding affinity to human lysosomal acid alpha-glucosidase assessed as inhibitio... | 37314161 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 37314161 | 10.1021/acs.jmedchem.3c00637 | Lysosomal alpha-glucosidase | 1 |
Data from ChEMBL 36 via Core Engine