Compound Detail
CHEMBL5400857
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Basic Information
| ChEMBL ID | CHEMBL5400857 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | KOKSZCCNTRXJJW-UHFFFAOYSA-N |
1
Targets
2
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
161.0
MW (Da)
Drug Information
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 2 meas. best 6.04
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Glutathione hydrolase 1 proenzyme CHEMBL5696 | Ki | 6.04 | 5.795 | 920.0 | 2 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Glutathione hydrolase 1 proenzyme | Ki | = | 920.0 | nM | 6.04 | Inhibition of GGT1 (unknown origin) transpeptidation assessed as inhibition cons... | 37423504 |
| Glutathione hydrolase 1 proenzyme | Ki | = | 2800.0 | nM | 5.55 | Inhibition of GGT1 (unknown origin) assessed as GSH hydrolysis by measuring inhi... | 37423504 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 37423504 | 10.1016/j.bmcl.2023.129406 | Glutathione hydrolase 1 proenzyme | 2 |
Data from ChEMBL 36 via Core Engine