Compound Detail
CHEMBL5408125
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL5408125 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | FVUBLAPDLPXPIT-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
2
Publications
0
Known Names
Molecular Properties
352.5
MW (Da)
3.04
ALogP
4
HBA
0
HBD
39.7
PSA (Ų)
0.77
QED
0
Ro5 Violations
7
Rot. Bonds
Drug Information
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
EC50 1 meas. best 6.2
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Mu-type opioid receptor CHEMBL233 | EC50 | 6.2 | 6.2 | 632.8 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Mu-type opioid receptor | EC50 | = | 632.8 | nM | 6.2 | Agonist activity at mu-opioid receptor (unknown origin) expressed in CHO cells a... | 38015878 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 38015878 | 10.1021/acs.jmedchem.3c01637 | Mu-type opioid receptor | 1 |
| 38015878 | 10.1021/acs.jmedchem.3c01637 | Sigma non-opioid intracellular receptor 1 | 1 |
Data from ChEMBL 36 via Core Engine