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Compound Detail

CHEMBL541169

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CC[N+]1(CCOC(=O)C(CO)c2ccccc2)CCCCC1

Basic Information

ChEMBL ID CHEMBL541169
Phase Preclinical
Structure Type MOL
InChI Key XKVJIEZQWRWRHD-UHFFFAOYSA-N

Known Names

BL-58125
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
1
Known Names

Molecular Properties

306.4
MW (Da)
2.33
ALogP
3
HBA
1
HBD
46.5
PSA (Ų)
0.62
QED
0
Ro5 Violations
7
Rot. Bonds

Drug Information

Molecule Type Small molecule
Availability Unknown
Chirality Unknown

Flags

First in Class Prodrug

Extended Properties

Molecular Formula C18H28NO3+
MW 306.43
Aromatic Rings 1
Heavy Atoms 22
NP-Likeness 0.19

Activity Summary

Ki 1 meas. best 8.7

Target Activity Profile

Target Type Best pChEMBL Mean pChEMBL Best (nM) # Data
Unchecked
CHEMBL612545
Ki 8.7 8.7 2.0 1

Activity Data Samples

Top measurements by pChEMBL value

Target Type Rel. Value Units pChEMBL Assay PubMed
Unchecked Ki = 1.995 nM 8.7 Inhibition of [3H]NMS binding to muscarinic receptor in mouse N4TG1 neuroblastom... 19409797

Literature References

PubMed DOI Target Context # Activities
19409797 10.1016/j.bmc.2009.04.001 Unchecked 1

Data from ChEMBL 36 via Core Engine