Compound Detail
CHEMBL5420211
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O=C(Nc1ccc(C(=O)Nc2cccc(C(=O)Nc3cc(S(=O)(=O)O)cc4cc(S(=O)(=O)O)cc(S(=O)(=O)O)c34)c2)cc1)Nc1ccc(C(=O)Nc2cccc(C(=O)Nc3cc(S(=O)(=O)O)cc4cc(S(=O)(=O)O)cc(S(=O)(=O)O)c34)c2)cc1
Basic Information
| ChEMBL ID | CHEMBL5420211 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | NJFHCMXKHJCYIP-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
2
Publications
0
Known Names
Molecular Properties
1269.2
MW (Da)
Drug Information
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
EC50 1 meas. best 4.77
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Unchecked CHEMBL612545 | EC50 | 4.77 | 4.77 | 17000.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Unchecked | EC50 | = | 17000.0 | nM | 4.77 | Induction of TIMP3 protein level in human HTB-94 cells incubated for 36 hrs by s... | 37517101 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 37517101 | 10.1016/j.bmc.2023.117424 | Unchecked | 3 |
| 37517101 | 10.1016/j.bmc.2023.117424 | SW1353 | 1 |
Data from ChEMBL 36 via Core Engine