Compound Detail
CHEMBL5422487
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL5422487 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | JUIIKCVXDUPZBI-RBSFLKMASA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
2
Publications
0
Known Names
Molecular Properties
333.4
MW (Da)
1.43
ALogP
4
HBA
3
HBD
63.9
PSA (Ų)
0.69
QED
0
Ro5 Violations
6
Rot. Bonds
Drug Information
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 1 meas. best 6.14
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Lysosomal alpha-glucosidase CHEMBL2608 | Ki | 6.14 | 6.14 | 730.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Lysosomal alpha-glucosidase | Ki | = | 730.0 | nM | 6.14 | Binding affinity to human lysosomal acid alpha-glucosidase assessed as inhibitio... | 37314161 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 37314161 | 10.1021/acs.jmedchem.3c00637 | Lysosomal alpha-glucosidase | 5 |
| 37314161 | 10.1021/acs.jmedchem.3c00637 | Unchecked | 1 |
Data from ChEMBL 36 via Core Engine