Compound Detail
CHEMBL5434345
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
CC(=O)N[C@@H](C)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@H](C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@H](C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CO)C(N)=O)C(C)C)[C@@H](C)O
Basic Information
| ChEMBL ID | CHEMBL5434345 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | YABWHPOODAWVRU-RETQXLQUSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
1237.4
MW (Da)
Drug Information
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 1 meas. best 9.57
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| WD repeat-containing protein 5 CHEMBL1075317 | Ki | 9.57 | 9.57 | 0.3 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| WD repeat-containing protein 5 | Ki | = | 0.27 | nM | 9.57 | Competitive inhibition of WDR5 (unknown origin) assessed as inhibition constant ... | 38389889 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 38389889 | 10.1039/d3md00605k | WD repeat-containing protein 5 | 2 |
Data from ChEMBL 36 via Core Engine