Compound Detail
CHEMBL5436044
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Basic Information
| ChEMBL ID | CHEMBL5436044 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | QFIRBTHRBCNMLO-UHFFFAOYSA-N |
2
Targets
2
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
397.3
MW (Da)
Drug Information
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 2 meas. best 8.78
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Xanthine dehydrogenase/oxidase CHEMBL1929 | IC50 | 8.78 | 8.78 | 1.7 | 1 |
| Xanthine dehydrogenase/oxidase CHEMBL3649 | IC50 | 8.78 | 8.78 | 1.7 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Xanthine dehydrogenase/oxidase | IC50 | = | 1.67 | nM | 8.78 | Inhibition of Bovine milk XO using xanthine as substrate assessed as decrease in... | 37974965 |
| Xanthine dehydrogenase/oxidase | IC50 | = | 1.67 | nM | 8.78 | Inhibition Assay: The inhibition of the activity of xanthine oxidase (XO) is tes... | - |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 37974965 | 10.1039/d3md00316g | Xanthine dehydrogenase/oxidase | 1 |
Data from ChEMBL 36 via Core Engine