Compound Detail
CHEMBL5439799
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Basic Information
| ChEMBL ID | CHEMBL5439799 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | UFKLYTOEMRFKAD-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
397.5
MW (Da)
2.48
ALogP
7
HBA
2
HBD
100.5
PSA (Ų)
0.82
QED
0
Ro5 Violations
4
Rot. Bonds
Drug Information
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 7.8
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Serine/threonine-protein kinase mTOR CHEMBL2842 | IC50 | 7.8 | 7.8 | 16.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Serine/threonine-protein kinase mTOR | IC50 | = | 16.0 | nM | 7.8 | Inhibition of mTOR (unknown origin) | 36462440 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 36462440 | 10.1016/j.ejmech.2022.114971 | Serine/threonine-protein kinase mTOR | 1 |
Data from ChEMBL 36 via Core Engine