Compound Detail
CHEMBL5439802
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Basic Information
| ChEMBL ID | CHEMBL5439802 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | VATFPEIPODKPJQ-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
2
Publications
0
Known Names
Molecular Properties
270.7
MW (Da)
3.24
ALogP
4
HBA
2
HBD
63.8
PSA (Ų)
0.55
QED
0
Ro5 Violations
2
Rot. Bonds
Drug Information
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 5.34
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Leishmania infantum CHEMBL612848 | IC50 | 5.34 | 5.34 | 4550.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Leishmania infantum | IC50 | = | 4550.0 | nM | 5.34 | Antileishmanial activity against Leishmania infantum promastigotes | 37859724 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 37859724 | 10.1039/d3md00243h | Trypanosoma cruzi | 2 |
| 37859724 | 10.1039/d3md00243h | Leishmania infantum | 1 |
Data from ChEMBL 36 via Core Engine