Compound Detail
CHEMBL54469
METHYLTRIPHENYLPHOSPHONIUM BROMIDE Enter ChEMBL ID:
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Basic Information
| ChEMBL ID | CHEMBL54469 |
| Name | METHYLTRIPHENYLPHOSPHONIUM BROMIDE |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | LSEFCHWGJNHZNT-UHFFFAOYSA-M |
| Parent Compound | CHEMBL1179021 |
| Active Moiety | CHEMBL1179021 |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
4
Publications
0
Known Names
Molecular Properties
277.3
MW (Da)
3.61
ALogP
0
HBA
0
HBD
0.0
PSA (Ų)
0.64
QED
0
Ro5 Violations
3
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 6.05
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Unchecked CHEMBL612545 | IC50 | 6.05 | 6.05 | 891.2 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Unchecked | IC50 | = | 891.25 | nM | 6.05 | Antagonism of carbachol action on nAChR of isolated frog rectus abdominus. | 11960498 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 26042548 | 10.1021/acs.jnatprod.5b00124 | Paracentrotus lividus | 4 |
| 7401115 | 10.1021/jm00182a010 | Schistosoma mansoni | 3 |
| 11960498 | 10.1021/jm011067f | Unchecked | 1 |
| 11960498 | 10.1021/jm011067f | Acetylcholine receptor | 1 |
Data from ChEMBL 36 via Core Engine