Compound Detail
CHEMBL5556078
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL5556078 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | FYGBEECEWWZAPY-UHFFFAOYSA-N |
2
Targets
2
Activities
1
Assay Types
0
PK Parameters
2
Publications
0
Known Names
Molecular Properties
493.9
MW (Da)
3.31
ALogP
6
HBA
2
HBD
97.0
PSA (Ų)
0.61
QED
0
Ro5 Violations
7
Rot. Bonds
Drug Information
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
EC50 2 meas. best 5.3
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Plasmodium falciparum CHEMBL364 | EC50 | 5.3 | 5.3 | 5000.0 | 1 |
| HepG2 CHEMBL395 | EC50 | 4.7 | 4.7 | 19800.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Plasmodium falciparum | EC50 | = | 5000.0 | nM | 5.3 | Antimalarial activity against asexual blood stage Plasmodium falciparum 3D7 asse... | 38554474 |
| HepG2 | EC50 | = | 19800.0 | nM | 4.7 | Cytotoxicity against human HepG2 cells assessed as reduction in cell viability i... | 38554474 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 38554474 | 10.1016/j.ejmech.2024.116354 | Plasmodium falciparum | 1 |
| 38554474 | 10.1016/j.ejmech.2024.116354 | HepG2 | 1 |
Data from ChEMBL 36 via Core Engine