Compound Detail
CHEMBL5565571
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Basic Information
| ChEMBL ID | CHEMBL5565571 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | TWZCNGRSWNFZKJ-UHFFFAOYSA-N |
| Parent Compound | CHEMBL6070138 |
| Active Moiety | CHEMBL6070138 |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
2
Publications
0
Known Names
Molecular Properties
265.4
MW (Da)
2.43
ALogP
4
HBA
1
HBD
61.5
PSA (Ų)
0.83
QED
0
Ro5 Violations
5
Rot. Bonds
Drug Information
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
EC50 1 meas. best 6.07
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| 5-hydroxytryptamine receptor 2A CHEMBL224 | EC50 | 6.07 | 6.07 | 850.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| 5-hydroxytryptamine receptor 2A | EC50 | = | 850.0 | nM | 6.07 | Agonist activity at human 5-HT2A receptor expressed in HEK293 cells assessed as ... | 38593423 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 38593423 | 10.1021/acs.jmedchem.3c01961 | 5-hydroxytryptamine receptor 2A | 1 |
| 38593423 | 10.1021/acs.jmedchem.3c01961 | No relevant target | 1 |
Data from ChEMBL 36 via Core Engine