Compound Detail
CHEMBL5570085
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C[C@@H]1N(C(=O)[C@@H](N)CCCNC(=N)N)C[C@@H](CCB(O)O)C[C@]1(N)C(=O)O
Basic Information
| ChEMBL ID | CHEMBL5570085 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | UBRMVDUSQBGUJV-USXUVBGUSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
386.3
MW (Da)
Drug Information
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 6.4
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Arginase-1 CHEMBL1075097 | IC50 | 6.4 | 6.4 | 400.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Arginase-1 | IC50 | = | 400.0 | nM | 6.4 | Inhibition of human recombinant ARG1 expressed in Escherichia coli using L-argin... | 38096651 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 38096651 | 10.1016/j.ejmech.2023.116033 | Arginase-1 | 1 |
Data from ChEMBL 36 via Core Engine