Compound Detail
CHEMBL5570349
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Basic Information
| ChEMBL ID | CHEMBL5570349 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | QOVWSBPGVCDKHB-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
418.3
MW (Da)
2.66
ALogP
6
HBA
1
HBD
57.9
PSA (Ų)
0.81
QED
0
Ro5 Violations
5
Rot. Bonds
Drug Information
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 9.05
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Serine/threonine-protein kinase pim-1 CHEMBL2147 | IC50 | 9.05 | 9.05 | 0.9 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Serine/threonine-protein kinase pim-1 | IC50 | = | 0.9 | nM | 9.05 | Inhibition of PIM1 (unknown origin) | 38164076 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 38164076 | 10.1021/acs.jmedchem.3c01802 | Serine/threonine-protein kinase pim-1 | 1 |
Data from ChEMBL 36 via Core Engine