Compound Detail
CHEMBL5570667
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Cc1ccc2nc(-c3ccc4nc(-c5ccc(NC(=O)c6cc(C(F)(F)F)cc(C(F)(F)F)c6)cc5)sc4c3)sc2c1S(=O)(=O)O
Basic Information
| ChEMBL ID | CHEMBL5570667 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | RBJJVQNOYYVWLF-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
693.7
MW (Da)
9.09
ALogP
7
HBA
2
HBD
109.2
PSA (Ų)
0.14
QED
2
Ro5 Violations
5
Rot. Bonds
Drug Information
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 8.3
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| RNA CHEMBL2363073 | IC50 | 8.3 | 8.3 | 5.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| RNA | IC50 | = | 5.0 | nM | 8.3 | Inhibition of Hepatitis C virus RNA | 38179950 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 38179950 | 10.1021/acs.jmedchem.3c01971 | RNA | 1 |
Data from ChEMBL 36 via Core Engine