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Target Snapshot

CHEMBL2363073 Target Snapshot

RNA · NUCLEIC-ACID · Hepacivirus hominis

1Compounds
1Assays
0Approved Drugs
1.0Activities
Free Research Context

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Broader Open DB context

Frame the target before identity details

Structured disease, protein, and project context should read before the lower-level identity rail.

As of 2026-09-13

RNA shows approved-linked disease relevance led by chronic hepatitis C virus infection. 5 more disease programs remain visible in the same review block. 1 linked drug keeps the current disease frame grounded. Use chronic hepatitis C virus infection as the disease frame, then confirm a stable protein accession before cross-source reuse.

Review focus
Disease frame ready

Use chronic hepatitis C virus infection as the disease frame, then confirm a stable protein accession before cross-source reuse.

ChEMBL component mapping + Open Targets-ready proxy + ChEMBL 36 via Core Engine 2026-09-13 1 linked drug
Open source guide
Disease program
chronic hepatitis C virus infection

RNA shows approved-linked disease relevance led by chronic hepatitis C virus infection. 5 more disease programs remain visible in the same review block. 1 linked drug remains visible in the same block.

Start review with chronic hepatitis C virus infection because it currently carries approved-linked support. Linked drugs include RIBAVIRIN. This disease block keeps the Open Targets-ready contract explicit while current evidence comes from ChEMBL mechanism and indication mappings.

Disease source · ChEMBL drug mechanism + indication proxy
Approved-linked Open Targets-ready proxy 1 linked drug
Open disease block
Identity Layer

Cross-source identity

Keep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.

This review treats RNA as ChEMBL target CHEMBL2363073. Disease framing currently uses the Open Targets-ready proxy contract.

Review anchor
RNA
NUCLEIC-ACID · Hepacivirus hominis
As of 2026-09-13
ChEMBL target ID
CHEMBL2363073
Primary anchor for compounds, assays, approvals, and exports
ChEMBL 36 via Core Engine As of 2026-09-13
www.ebi.ac.uk
Disease evidence contract
Open Targets-ready proxy
ChEMBL drug mechanism + indication proxy
ChEMBL drug mechanism + indication proxy As of 2026-09-13
www.ebi.ac.uk

Reuse the same identifiers in notes, watch rules, exports, and review packs so provenance stays stable across surfaces.

Source Guidance

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Choose the first block or source based on the question you are trying to answer.

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UniProt Target Context
UniProt accession via ChEMBL component mapping

Start here when your first question is whether RNA still has a stable protein naming contract across sources.

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Need disease fit before discussing compounds?
Disease Relevance & Evidence Level
ChEMBL drug mechanism + indication proxy

Use this block first when you need to confirm why chronic hepatitis C virus infection is currently framed as approved-linked support. It currently carries 1 linked drug in the same disease frame.

Jump to Disease Context
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Evidence Card
Review-ready rationale with source-aware context

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Overview

Basic Information

Verify identity, organism, and the fastest next research jumps from the same page.

UniProt Context

UniProt Target Context

Reviewable protein naming and mapping context for this target snapshot.

Protein LabelRNA
UniProt AccessionN/A

RNA

Source · UniProt accession via ChEMBL component mapping
Review Cue

How to read this target

Review this target as RNA.

Review nameRNA
OrganismHepacivirus hominis
Disease Relevance

Disease Relevance & Evidence Level

Open Targets-ready disease context using the current target-indication evidence contract.

Approved-linked Open Targets-ready proxy

RNA shows approved-linked disease relevance led by chronic hepatitis C virus infection. 5 more disease programs remain visible in the same review block.

Approved-linked Approved
chronic hepatitis C virus infection
1 linked drug · 1 direct · 1 efficacy
Linked drugRIBAVIRIN
Approved-linked Approved
cirrhosis of liver
1 linked drug · 1 direct · 1 efficacy
Linked drugRIBAVIRIN
Approved-linked Approved
cirrhosis of liver
1 linked drug · 1 direct · 1 efficacy
Linked drugRIBAVIRIN
Approved-linked Approved
fibrosis
1 linked drug · 1 direct · 1 efficacy
Linked drugRIBAVIRIN
Approved-linked Approved
viral disease
1 linked drug · 1 direct · 1 efficacy
Linked drugRIBAVIRIN
Late clinical Phase III
chronic hepatitis B virus infection
1 linked drug · 1 direct · 1 efficacy
Linked drugRIBAVIRIN
Source · ChEMBL drug mechanism + indication proxy
Review Cue

How to read disease relevance

Start review with chronic hepatitis C virus infection because it currently carries approved-linked support. Linked drugs include RIBAVIRIN. This disease block keeps the Open Targets-ready contract explicit while current evidence comes from ChEMBL mechanism and indication mappings.

Lead diseasechronic hepatitis C virus infection
Strongest levelApproved-linked
Block modeOpen Targets-ready proxy
Assay Mix

Activity Type Distribution

IC501.0
Lead Set

Top Inhibitors (by pChEMBL)

ChEMBL IDpChEMBLTypeValue (nM)Phase
CHEMBL5570667 8.3 IC50 5.0 Preclinical
Distribution

pChEMBL Value Distribution

0
5.0
0
5.5
0
6.0
0
6.5
0
7.0
0
7.5
1
8.0
0
8.5
0
9.0
0
9.5
pChEMBL
Assay Landscape

Assay Landscape

1
Total Assays
1
Tested Compounds
1
Assay Types
Binding — 1 assays, 1 compounds
BAO Format Assays Compounds Avg pChEMBL
nucleic acid format 1 1 8.3

Confidence Score Distribution

Source · ChEMBL 36 via Core Engine