Compound Detail
CHEMBL5571474
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL5571474 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | YHBXKWORQOPSHI-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
269.3
MW (Da)
2.87
ALogP
2
HBA
2
HBD
66.4
PSA (Ų)
0.90
QED
0
Ro5 Violations
4
Rot. Bonds
Drug Information
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
EC50 1 meas. best 7.1
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Free fatty acid receptor 1 CHEMBL4422 | EC50 | 7.1 | 7.1 | 80.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Free fatty acid receptor 1 | EC50 | = | 80.0 | nM | 7.1 | Agonist activity at human GPR40 stably expressed in CHO cells assessed as increa... | 38039791 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 38039791 | 10.1016/j.ejmech.2023.115990 | Free fatty acid receptor 1 | 1 |
Data from ChEMBL 36 via Core Engine