Compound Detail
CHEMBL5573266
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Basic Information
| ChEMBL ID | CHEMBL5573266 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | UALQGVFKHLQMKV-AHAZDQFESA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
2
Publications
0
Known Names
Molecular Properties
392.6
MW (Da)
5.27
ALogP
4
HBA
2
HBD
66.8
PSA (Ų)
0.20
QED
1
Ro5 Violations
17
Rot. Bonds
Drug Information
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
EC50 1 meas. best 7.46
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Cannabinoid receptor 1 CHEMBL3571 | EC50 | 7.46 | 7.46 | 34.6 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Cannabinoid receptor 1 | EC50 | = | 34.6 | nM | 7.46 | Agonist activity at rat CB1 receptor stably expressed in HEK293 cells assessed a... | 38894922 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 38894922 | 10.1021/acsmedchemlett.4c00175 | Cannabinoid receptor 1 | 2 |
| 38894922 | 10.1021/acsmedchemlett.4c00175 | Cannabinoid receptor 2 | 2 |
Data from ChEMBL 36 via Core Engine