Compound Detail
CHEMBL5584133
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Basic Information
| ChEMBL ID | CHEMBL5584133 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | AVBQMCJQNFJMRX-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
382.5
MW (Da)
4.04
ALogP
6
HBA
1
HBD
73.5
PSA (Ų)
0.73
QED
0
Ro5 Violations
7
Rot. Bonds
Drug Information
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 4.07
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Spindlin-1 CHEMBL4523509 | IC50 | 4.07 | 4.07 | 84300.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Spindlin-1 | IC50 | = | 84300.0 | nM | 4.07 | Displacement of FL-H3K4me3 peptide from human N-terminal His10 tagged SPIN1 (G21... | 38533580 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 38533580 | 10.1021/acs.jmedchem.4c00121 | Spindlin-1 | 1 |
Data from ChEMBL 36 via Core Engine