Compound Detail
CHEMBL5592337
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Basic Information
| ChEMBL ID | CHEMBL5592337 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | VQCSXHRKVKJOPB-UHFFFAOYSA-N |
1
Targets
2
Activities
2
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
370.2
MW (Da)
1.69
ALogP
6
HBA
3
HBD
98.5
PSA (Ų)
0.76
QED
0
Ro5 Violations
3
Rot. Bonds
Drug Information
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
EC50 1 meas.
Kd 1 meas. best 5.11
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Internal ribosome entry site (IRES) CHEMBL612412 | Kd | 5.11 | 5.11 | 7800.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Internal ribosome entry site (IRES) | Kd | = | 7800.0 | nM | 5.11 | Binding affinity to HCV IRES subdomain IIa RNA assessed as dissociation constant... | 38784459 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 38784459 | 10.1039/d3md00696d | Internal ribosome entry site (IRES) | 2 |
Data from ChEMBL 36 via Core Engine