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Compound Detail

CHEMBL5593204

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F[B-]1(F)n2c(cc3sc4ccsc4c32)C(c2ccccc2)=C2C=c3sc4ccsc4c3=[N+]21

Basic Information

ChEMBL ID CHEMBL5593204
Phase Preclinical
Structure Type MOL
InChI Key ONEOQQPZKMZVJM-UHFFFAOYSA-N
1
Targets
2
Activities
1
Assay Types
0
PK Parameters
3
Publications
0
Known Names

Molecular Properties

492.4
MW (Da)

Drug Information

Availability Unknown
Chirality Unknown

Flags

First in Class Prodrug

Extended Properties

Molecular Formula C23H11BF2N2S4
MW 492.43

Activity Summary

IC50 2 meas. best 5.52

Target Activity Profile

Target Type Best pChEMBL Mean pChEMBL Best (nM) # Data
ECa-109 cell line
CHEMBL614668
IC50 5.52 5.32 3020.0 2

Activity Data Samples

Top measurements by pChEMBL value

Literature References

PubMed DOI Target Context # Activities
38056302 10.1016/j.ejmech.2023.116012 No relevant target 2
38056302 10.1016/j.ejmech.2023.116012 ECa-109 cell line 2
38056302 10.1016/j.ejmech.2023.116012 Unchecked 1

Data from ChEMBL 36 via Core Engine