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Compound Detail

CHEMBL5596765

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CC(C)[C@@]12CC[C@]3(C)[C@]4(Cc5c6c(c(O)c(Cl)c5O[C@]4(C)CC[C@]3(O)O1)C(=O)O[C@H](C)C6)O2

Basic Information

ChEMBL ID CHEMBL5596765
Phase Preclinical
Structure Type MOL
InChI Key XNJCLRDLXMKZRA-WPWFMLIPSA-N
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names

Molecular Properties

479.0
MW (Da)
4.26
ALogP
7
HBA
2
HBD
94.5
PSA (Ų)
0.58
QED
0
Ro5 Violations
1
Rot. Bonds

Drug Information

Availability Unknown
Chirality Unknown

Flags

First in Class Prodrug

Extended Properties

Molecular Formula C25H31ClO7
MW 478.97
Aromatic Rings 1
Heavy Atoms 33
NP-Likeness 1.88

Activity Summary

IC50 1 meas. best 6.75

Target Activity Profile

Target Type Best pChEMBL Mean pChEMBL Best (nM) # Data
Vesicular stomatitis virus
CHEMBL613739
IC50 6.75 6.75 180.0 1

Activity Data Samples

Top measurements by pChEMBL value

Literature References

PubMed DOI Target Context # Activities
39126395 10.1021/acs.jnatprod.4c00539 Vesicular stomatitis virus 1

Data from ChEMBL 36 via Core Engine