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Compound Detail

CHEMBL5596902

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CC(=O)O[C@@H]1c2c3c(cc(O)c2C(=O)O[C@@H]1C)O[C@]1(C)CC[C@@H]2O[C@@]4(C(C)C)CC[C@]2(C)[C@]1(C3)O4

Basic Information

ChEMBL ID CHEMBL5596902
Phase Preclinical
Structure Type MOL
InChI Key GVGJEVWMZNUQLE-BUAFFRTESA-N
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names

Molecular Properties

486.6
MW (Da)
4.35
ALogP
8
HBA
1
HBD
100.5
PSA (Ų)
0.62
QED
0
Ro5 Violations
2
Rot. Bonds

Drug Information

Availability Unknown
Chirality Unknown

Flags

First in Class Prodrug

Extended Properties

Molecular Formula C27H34O8
MW 486.56
Aromatic Rings 1
Heavy Atoms 35
NP-Likeness 2.38

Activity Summary

IC50 1 meas. best 6.31

Target Activity Profile

Target Type Best pChEMBL Mean pChEMBL Best (nM) # Data
Vesicular stomatitis virus
CHEMBL613739
IC50 6.31 6.31 490.0 1

Activity Data Samples

Top measurements by pChEMBL value

Literature References

PubMed DOI Target Context # Activities
39126395 10.1021/acs.jnatprod.4c00539 Vesicular stomatitis virus 1

Data from ChEMBL 36 via Core Engine