Compound Detail
CHEMBL5597780
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Basic Information
| ChEMBL ID | CHEMBL5597780 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | YXBOHBFXBZXNRS-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
2
Publications
0
Known Names
Molecular Properties
418.3
MW (Da)
3.84
ALogP
3
HBA
2
HBD
61.4
PSA (Ų)
0.80
QED
0
Ro5 Violations
3
Rot. Bonds
Drug Information
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 6.36
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Inositol hexakisphosphate kinase 1 CHEMBL4523418 | IC50 | 6.36 | 6.36 | 440.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Inositol hexakisphosphate kinase 1 | IC50 | = | 440.0 | nM | 6.36 | Inhibition of IP6K1 (unknown origin) using IP6 as substrate incubated for 30 min... | 39096294 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 39096294 | 10.1021/acs.jmedchem.4c00190 | Inositol hexakisphosphate kinase 1 | 1 |
| 39096294 | 10.1021/acs.jmedchem.4c00190 | ADMET | 1 |
Data from ChEMBL 36 via Core Engine