Compound Detail
CHEMBL563014
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL563014 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | FJTFXYXTBVCQSP-PBHICJAKSA-N |
1
Targets
2
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
331.3
MW (Da)
3.74
ALogP
2
HBA
0
HBD
6.5
PSA (Ų)
0.79
QED
0
Ro5 Violations
1
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 2 meas. best 6.74
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Histamine H3 receptor CHEMBL264 | Ki | 6.74 | 6.74 | 182.0 | 2 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Histamine H3 receptor | Ki | = | 181.97 | nM | 6.74 | Displacement of [3H]N-alpha methyl histamine from human cloned histamine H3 rece... | 19588934 |
| Histamine H3 receptor | Ki | = | 182.0 | nM | 6.74 | Displacement of [3H]N-alpha methyl histamine from human cloned histamine H3 rece... | 19588934 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 19588934 | 10.1021/jm900480x | Histamine H3 receptor | 4 |
Data from ChEMBL 36 via Core Engine