Compound Detail
CHEMBL566055
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Basic Information
| ChEMBL ID | CHEMBL566055 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | RIWHHKIQQIRFCQ-PKTZIBPZSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
539.6
MW (Da)
5.35
ALogP
8
HBA
3
HBD
154.6
PSA (Ų)
0.07
QED
2
Ro5 Violations
26
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
EC50 1 meas. best 5.7
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Mast cell CHEMBL613709 | EC50 | 5.7 | 5.7 | 2000.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Mast cell | EC50 | = | 2000.0 | nM | 5.7 | Induction of Wistar rat peritoneal mast cell degradation assessed as concanavali... | 19743861 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 19743861 | 10.1021/jm900598m | Mast cell | 2 |
Data from ChEMBL 36 via Core Engine