Compound Detail
CHEMBL566590
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL566590 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | DOFNBYNJSFTVKW-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
343.2
MW (Da)
3.63
ALogP
4
HBA
2
HBD
63.8
PSA (Ų)
0.71
QED
0
Ro5 Violations
4
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 6.68
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Unchecked CHEMBL612545 | IC50 | 6.68 | 6.68 | 207.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Unchecked | IC50 | = | 207.0 | nM | 6.68 | Inhibition of NF-kappaB activation | 19726185 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 19726185 | 10.1016/j.bmcl.2009.08.021 | Unchecked | 1 |
Data from ChEMBL 36 via Core Engine