Compound Detail
CHEMBL569069
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Basic Information
| ChEMBL ID | CHEMBL569069 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | PHZBXHVEFIDZFW-STQMWFEESA-N |
1
Targets
4
Activities
1
Assay Types
0
PK Parameters
2
Publications
0
Known Names
Molecular Properties
274.3
MW (Da)
0.78
ALogP
3
HBA
2
HBD
69.6
PSA (Ų)
0.84
QED
0
Ro5 Violations
2
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 4 meas. best 6.99
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| NON-PROTEIN TARGET CHEMBL3879801 | IC50 | 6.99 | 6.5025 | 103.0 | 4 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| NON-PROTEIN TARGET | IC50 | = | 103.0 | nM | 6.99 | Antiplatelet aggregatory activity in pig platelet poor plasma assessed as inhibi... | 19729231 |
| NON-PROTEIN TARGET | IC50 | = | 185.0 | nM | 6.73 | Antiplatelet aggregatory activity in pig platelet poor plasma assessed as inhibi... | 19729231 |
| NON-PROTEIN TARGET | IC50 | = | 364.0 | nM | 6.44 | Antiplatelet aggregatory activity in pig platelet poor plasma assessed as inhibi... | 19729231 |
| NON-PROTEIN TARGET | IC50 | = | 1398.0 | nM | 5.85 | Antiplatelet aggregatory activity in pig platelet poor plasma assessed as inhibi... | 19729231 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 19729231 | 10.1016/j.ejmech.2009.08.002 | NON-PROTEIN TARGET | 4 |
| 19729231 | 10.1016/j.ejmech.2009.08.002 | Rattus norvegicus | 2 |
Data from ChEMBL 36 via Core Engine