Compound Detail
CHEMBL571063
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL571063 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | SQRKOAHICBTYND-ZANVPECISA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
297.2
MW (Da)
4.26
ALogP
2
HBA
1
HBD
52.9
PSA (Ų)
0.89
QED
0
Ro5 Violations
2
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
EC50 1 meas. best 5.7
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Metabotropic glutamate receptor 4 CHEMBL2736 | EC50 | 5.7 | 5.7 | 2000.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Metabotropic glutamate receptor 4 | EC50 | = | 2000.0 | nM | 5.7 | Allosteric modulator activity at human mGlu4 receptor expressed in CHO cells coe... | 19640716 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 19640716 | 10.1016/j.bmcl.2009.07.072 | Metabotropic glutamate receptor 4 | 2 |
Data from ChEMBL 36 via Core Engine