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Compound Detail

CHEMBL571449

SODIUM LINOLATE
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CCCCC/C=C\C/C=C\CCCCCCCC(=O)[O-].[Na+]

Basic Information

ChEMBL ID CHEMBL571449
Name SODIUM LINOLATE
Phase Preclinical
Structure Type MOL
InChI Key WYPBVHPKMJYUEO-NBTZWHCOSA-M
Parent Compound CHEMBL267476
Active Moiety CHEMBL267476
1
Targets
2
Activities
2
Assay Types
0
PK Parameters
3
Publications
0
Known Names

Molecular Properties

280.4
MW (Da)
5.88
ALogP
1
HBA
1
HBD
37.3
PSA (Ų)
0.32
QED
1
Ro5 Violations
14
Rot. Bonds

Drug Information

Molecule Type Small molecule
Availability Unknown
Chirality Unknown

Flags

First in Class Prodrug

Extended Properties

Molecular Formula C18H31NaO2
MW 302.43
Aromatic Rings 0
Heavy Atoms 20
NP-Likeness 1.19

Activity Summary

Kd 1 meas.
Ki 1 meas. best 4.87

Target Activity Profile

Target Type Best pChEMBL Mean pChEMBL Best (nM) # Data
Cytochrome P450 1A2
CHEMBL1075125
Ki 4.87 4.87 13600.0 1

Activity Data Samples

Top measurements by pChEMBL value

Target Type Rel. Value Units pChEMBL Assay PubMed
Cytochrome P450 1A2 Ki = 13600.0 nM 4.87 Competitive inhibition of rat recombinant CYP1A2 expressed in Escherichia coli a... 22331994

Literature References

PubMed DOI Target Context # Activities
17954701 10.1128/aac.01009-07 NON-PROTEIN TARGET 4
17954701 10.1128/aac.01009-07 Unchecked 1
22331994 10.1124/dmd.111.044057 Cytochrome P450 1A2 1

Data from ChEMBL 36 via Core Engine