Compound Detail
CHEMBL571637
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Basic Information
| ChEMBL ID | CHEMBL571637 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | VFXKLEZTLGQSMY-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
2
Publications
0
Known Names
Molecular Properties
427.5
MW (Da)
5.72
ALogP
5
HBA
1
HBD
76.7
PSA (Ų)
0.43
QED
1
Ro5 Violations
6
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 6.23
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Unchecked CHEMBL612545 | IC50 | 6.23 | 6.23 | 590.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Unchecked | IC50 | = | 590.0 | nM | 6.23 | Inhibition of HCV recombinant NS5B Cdelta21 RdRp expressed in Escherichia coli a... | 19819138 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 19819138 | 10.1016/j.bmcl.2009.09.087 | Unchecked | 1 |
| 19819138 | 10.1016/j.bmcl.2009.09.087 | Hepatitis C virus | 1 |
Data from ChEMBL 36 via Core Engine