Compound Detail
CHEMBL572289
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL572289 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | ORGIEVJOOKKXIL-JXMROGBWSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
3
Publications
0
Known Names
Molecular Properties
342.4
MW (Da)
4.09
ALogP
5
HBA
1
HBD
65.0
PSA (Ų)
0.58
QED
0
Ro5 Violations
8
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 4.92
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Unchecked CHEMBL612545 | IC50 | 4.92 | 4.92 | 12000.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Unchecked | IC50 | = | 12000.0 | nM | 4.92 | Inhibition of cobalt chloride-induced HIF-1 activation expressed in mouse NIH3T3... | 21112783 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 19883086 | 10.1021/jm901278z | Unchecked | 1 |
| 21112783 | 10.1016/j.bmcl.2010.10.063 | Unchecked | 1 |
| 21112783 | 10.1016/j.bmcl.2010.10.063 | ADMET | 1 |
Data from ChEMBL 36 via Core Engine