Compound Detail
CHEMBL573221
RAC-DICHLORPROP Enter ChEMBL ID:
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Basic Information
| ChEMBL ID | CHEMBL573221 |
| Name | RAC-DICHLORPROP |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | MZHCENGPTKEIGP-UHFFFAOYSA-N |
2
Targets
2
Activities
1
Assay Types
0
PK Parameters
6
Publications
0
Known Names
Molecular Properties
235.1
MW (Da)
2.85
ALogP
2
HBA
1
HBD
46.5
PSA (Ų)
0.88
QED
0
Ro5 Violations
3
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 2 meas. best 5.28
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Unchecked CHEMBL612545 | IC50 | 5.28 | 5.28 | 5300.0 | 1 |
| Trypanosoma cruzi CHEMBL368 | IC50 | 4.13 | 4.13 | 73950.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Unchecked | IC50 | = | 5300.0 | nM | 5.28 | Antagonist activity at human T1R2/T1R3 receptor expressed in HEK293E cells asses... | 19817384 |
| Trypanosoma cruzi | IC50 | = | 73950.0 | nM | 4.13 | DNDI: Inhibition of Chagas Disease parasite Trypanosoma cruzi (Tulahuen LacZ, Cl... | - |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 21401104 | 10.1021/jf200213z | Zea mays | 24 |
| 19817384 | 10.1021/jm900823s | Unchecked | 2 |
| 30289721 | 10.1021/acs.jmedchem.8b00859 | GABA-A receptor; alpha-1/beta-3/gamma-2 | 2 |
| - | 10.6019/CHEMBL4651402 | SARS-CoV-2 | 2 |
| - | 10.6019/CHEMBL1862790 | Trypanosoma cruzi | 1 |
| - | 10.6019/CHEMBL1862790 | L6 | 1 |
Data from ChEMBL 36 via Core Engine