Compound Detail
CHEMBL5740755
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
C=CS(=O)(=O)C(c1ccc(NC(=O)[C@@](C)(O)CS(=O)(=O)c2ccc(F)cc2)cc1C(F)(F)F)S(=O)(=O)C=C
Basic Information
| ChEMBL ID | CHEMBL5740755 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | VDCHZKBSZBNQDI-NRFANRHFSA-N |
1
Targets
2
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
599.6
MW (Da)
3.12
ALogP
8
HBA
2
HBD
151.8
PSA (Ų)
0.31
QED
1
Ro5 Violations
10
Rot. Bonds
Drug Information
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 2 meas. best 6.24
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Androgen receptor CHEMBL1871 | IC50 | 6.24 | 6.065 | 580.0 | 2 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Androgen receptor | IC50 | = | 580.0 | nM | 6.24 | Gal4-luciferase reporter assay: Briefly, the AR LBD is expressed as a fusion wit... | - |
| Androgen receptor | IC50 | = | 1290.0 | nM | 5.89 | mmTV-luciferase reporter assay: An AR-response element is contained within the m... | - |
Data from ChEMBL 36 via Core Engine