Compound Detail
CHEMBL5748871
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Basic Information
| ChEMBL ID | CHEMBL5748871 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | FTXIGEWEWBLIQK-CYBMUJFWSA-N |
2
Targets
3
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
415.5
MW (Da)
2.42
ALogP
7
HBA
3
HBD
119.9
PSA (Ų)
0.44
QED
0
Ro5 Violations
4
Rot. Bonds
Drug Information
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 3 meas. best 4.64
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Ribosomal protein S6 kinase alpha-3 CHEMBL2345 | IC50 | 4.64 | 4.64 | 23000.0 | 1 |
| Ribosomal protein S6 kinase alpha-2 CHEMBL3906 | IC50 | 4.64 | 4.64 | 23000.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Ribosomal protein S6 kinase alpha-3 | IC50 | = | 23000.0 | nM | 4.64 | Radioisotope assay: The assay was initiated by the addition of 33P-ATP and the r... | - |
| Ribosomal protein S6 kinase alpha-2 | IC50 | = | 23000.0 | nM | 4.64 | Kinase Assay: Radioisotope assays (SignalChem) were performed for the evaluation... | - |
Data from ChEMBL 36 via Core Engine