Compound Detail
CHEMBL5749239
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Basic Information
| ChEMBL ID | CHEMBL5749239 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | VSOFUQZXXJPURY-AWEZNQCLSA-N |
1
Targets
2
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
423.5
MW (Da)
2.18
ALogP
7
HBA
2
HBD
121.4
PSA (Ų)
0.60
QED
0
Ro5 Violations
7
Rot. Bonds
Drug Information
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 2 meas. best 8.96
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Interleukin-1 receptor-associated kinase 4 CHEMBL3778 | IC50 | 8.96 | 8.695 | 1.1 | 2 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Interleukin-1 receptor-associated kinase 4 | IC50 | = | 1.1 | nM | 8.96 | IRAK4 Enzymatic DELFIA Assay, Protocol B: This is an in vitro assay to measure I... | - |
| Interleukin-1 receptor-associated kinase 4 | IC50 | = | 3.7 | nM | 8.43 | IRAK4 Enzymatic DELFIA Assay, Protocol A: This is an in vitro assay to measure I... | - |
Data from ChEMBL 36 via Core Engine