Compound Detail
CHEMBL5758659
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Basic Information
| ChEMBL ID | CHEMBL5758659 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | OMKHWTRUYNAGFG-JROPRLTOSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
262.3
MW (Da)
-0.79
ALogP
7
HBA
4
HBD
117.4
PSA (Ų)
0.53
QED
0
Ro5 Violations
2
Rot. Bonds
Drug Information
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 8.03
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| AdoHcyase_NAD domain-containing protein CHEMBL4295548 | IC50 | 8.03 | 8.03 | 9.3 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| AdoHcyase_NAD domain-containing protein | IC50 | = | 9.3 | nM | 8.03 | S-Adenosylhomocysteine Hydrolase (SAHase) Inhibition: As a consequence of "D"-Is... | - |
Data from ChEMBL 36 via Core Engine