AdoHcyase_NAD domain-containing protein · SINGLE PROTEIN · Oryctolagus cuniculus
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As of 2026-09-14Protein identity stays anchored to UniProt G1SVH0. Use UniProt G1SVH0 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt G1SVH0 as the stable identity anchor, then attach disease evidence before program review.
Adenosylhomocysteinase
Review this target as AdoHcyase_NAD domain-containing protein, mapped to UniProt G1SVH0. ChEMBL maps the protein component as Adenosylhomocysteinase. Sequence length is 536 aa.
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This review treats AdoHcyase_NAD domain-containing protein as ChEMBL target CHEMBL4295548, mapped to UniProt G1SVH0. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | AdoHcyase_NAD domain-containing protein |
| Target Type | SINGLE PROTEIN |
| Organism | Oryctolagus cuniculus |
| UniProt | G1SVH0 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Adenosylhomocysteinase |
| UniProt Accession | G1SVH0 |
| Component Type | Protein |
| Sequence Length | 536 aa |
Adenosylhomocysteinase
Review this target as AdoHcyase_NAD domain-containing protein, mapped to UniProt G1SVH0. ChEMBL maps the protein component as Adenosylhomocysteinase. Sequence length is 536 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL3334763 | 9.05 | IC50 | 0.9 | Preclinical |
| CHEMBL2059155 | 8.57 | IC50 | 2.7 | Preclinical |
| CHEMBL154745 | 8.5 | IC50 | 3.19 | Preclinical |
| CHEMBL4285617 | 8.06 | IC50 | 8.69 | Preclinical |
| CHEMBL5758659 | 8.03 | IC50 | 9.3 | Preclinical |
| CHEMBL5847958 | 7.57 | IC50 | 27.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| assay format | 2 | 6 | 8.3 |