Compound Detail
CHEMBL576033
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Basic Information
| ChEMBL ID | CHEMBL576033 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | BVRCPMXFRMVPNG-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
4
Publications
0
Known Names
Molecular Properties
265.3
MW (Da)
2.38
ALogP
3
HBA
2
HBD
74.8
PSA (Ų)
0.56
QED
0
Ro5 Violations
3
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
EC50 1 meas. best 6.1
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| NON-PROTEIN TARGET CHEMBL3879801 | EC50 | 6.1 | 6.1 | 790.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| NON-PROTEIN TARGET | EC50 | = | 790.0 | nM | 6.1 | Antiprion activity against Scrapie prion protein-mediated scrapie in mouse SMB c... | 19842664 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 19842664 | 10.1021/jm900920x | NON-PROTEIN TARGET | 2 |
| 19682911 | 10.1016/j.bmc.2009.07.048 | NON-PROTEIN TARGET | 1 |
| 19682911 | 10.1016/j.bmc.2009.07.048 | L1210 | 1 |
| 19682911 | 10.1016/j.bmc.2009.07.048 | SK-OV-3 | 1 |
Data from ChEMBL 36 via Core Engine