Compound Detail
CHEMBL5762887
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL5762887 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | NSSGTCVEOJUPIH-SDBXPKJASA-N |
2
Targets
3
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
334.1
MW (Da)
Drug Information
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 3 meas. best 6.2
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Arginase-1 CHEMBL1075097 | IC50 | 6.2 | 6.2 | 625.0 | 2 |
| Arginase-2, mitochondrial CHEMBL1795148 | IC50 | 5.82 | 5.82 | 1500.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Arginase-1 | IC50 | = | 625.0 | nM | 6.2 | Inhibition Assay of Arginase: Inhibition of arginase I (ARG I) and arginase II (... | - |
| Arginase-1 | IC50 | = | 625.0 | nM | 6.2 | Inhibition of Arginase: Inhibition of arginase I (ARG I) and arginase II (ARG II... | - |
| Arginase-2, mitochondrial | IC50 | = | 1500.0 | nM | 5.82 | Inhibition Assay of Arginase: Inhibition of arginase I (ARG I) and arginase II (... | - |
Data from ChEMBL 36 via Core Engine