Arginase-2, mitochondrial · SINGLE PROTEIN · Homo sapiens
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As of 2026-09-14Protein identity stays anchored to UniProt P78540. Use UniProt P78540 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P78540 as the stable identity anchor, then attach disease evidence before program review.
Arginase-2, mitochondrial
Review this target as Arginase-2, mitochondrial, mapped to UniProt P78540. Sequence length is 354 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Arginase-2, mitochondrial as ChEMBL target CHEMBL1795148, mapped to UniProt P78540. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Arginase-2, mitochondrial |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | P78540 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Arginase-2, mitochondrial |
| UniProt Accession | P78540 |
| Component Type | Protein |
| Sequence Length | 354 aa |
Arginase-2, mitochondrial
Review this target as Arginase-2, mitochondrial, mapped to UniProt P78540. Sequence length is 354 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL4764455 | 10.0 | IC50 | 0.1 | Preclinical |
| CHEMBL4745275 | 8.4 | IC50 | 4.0 | Preclinical |
| CHEMBL1812661 | 8.07 | IC50 | 8.5 | Preclinical |
| CHEMBL1812661 | 8.07 | Ki | 8.5 | Preclinical |
| CHEMBL5723327 | 8.07 | Ki | 8.5 | Preclinical |
| CHEMBL4749355 | 8.0 | IC50 | 10.0 | Preclinical |
| CHEMBL5807059 | 8.0 | IC50 | 10.0 | Preclinical |
| CHEMBL4757930 | 7.82 | IC50 | 15.0 | Preclinical |
| CHEMBL4752307 | 7.7 | IC50 | 20.0 | Preclinical |
| CHEMBL4752391 | 7.68 | IC50 | 21.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 19 | 142 | 6.0 |
| assay format | 5 | 26 | 6.7 |
| cell-based format | 2 | 2 | 4.9 |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| assay format | 3 | 2 | 7.3 |