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Compound Detail

CHEMBL5807059

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CN[C@H]1CN[C@](CCCCB(O)O)(C(=O)O)C1

Basic Information

ChEMBL ID CHEMBL5807059
Phase Preclinical
Structure Type MOL
InChI Key ALIDHAHGIJCPSV-SCZZXKLOSA-N
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names

Molecular Properties

244.1
MW (Da)

Drug Information

Availability Unknown
Chirality Unknown

Flags

First in Class Prodrug

Extended Properties

Molecular Formula C10H21BN2O4
MW 244.10

Activity Summary

IC50 1 meas. best 8.0

Target Activity Profile

Target Type Best pChEMBL Mean pChEMBL Best (nM) # Data
Arginase-2, mitochondrial
CHEMBL1795148
IC50 8.0 8.0 10.0 1

Activity Data Samples

Top measurements by pChEMBL value

Target Type Rel. Value Units pChEMBL Assay PubMed
Arginase-2, mitochondrial IC50 = 10.0 nM 8.0 Biological Activity of Examples 1 to 30: The inhibitory effects of Examples 1 to... -

Data from ChEMBL 36 via Core Engine