Compound Detail
CHEMBL5775099
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Basic Information
| ChEMBL ID | CHEMBL5775099 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | HEMGSPAHKAXCSD-UHFFFAOYSA-N |
1
Targets
2
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
514.6
MW (Da)
3.56
ALogP
10
HBA
1
HBD
93.5
PSA (Ų)
0.32
QED
1
Ro5 Violations
11
Rot. Bonds
Drug Information
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 2 meas. best 8.12
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Activin receptor type-1 CHEMBL5903 | IC50 | 8.12 | 8.05 | 7.5 | 2 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Activin receptor type-1 | IC50 | = | 7.5 | nM | 8.12 | Enzyme Inhibitory Assay: R206H: An overview of evaluation of an inhibitory effec... | - |
| Activin receptor type-1 | IC50 | = | 10.4 | nM | 7.98 | Enzyme Inhibitory Assay: TABLE 5: An overview of evaluation of an inhibitory eff... | - |
Data from ChEMBL 36 via Core Engine